NOVEL THINKING

While word related presentation limits have not been set up, benzoic acid may, in any case, represent a wellbeing risk and, in this way, the safe work practices ought to consistently be followed: The exposure estimates in the regulatory maximum level exposure assessment scenario exceeded the acceptable daily intake (ADI) of 5 mg/kg body weight per day for all population groups at the high levels and for toddlers and children also at the mean level. ... there are still some concerns with the benzoic acid safety profile.

White crystalline powder. 05%). December 2013. Eliminate possible spark sources before using an approved vacuum to clean the spill. 2009;20:414–418. Preparation of potassium benzoate. (Forty sixth meeting of the Joint FAO/WHO Expert Meeting on Food Additives. Considering additional exposure from food categories which may contain benzoic acid-benzoates due to carry-over and for which data were available, the Panel concluded that exposure to benzoic acid-benzoates could be increased by up to two to three fold for all high-level consumers compared to the previous scenario for direct addition to food. Food Additive Status List. The location should be away from heat or possible sparks. Reaction by-products include benzaldehyde, acetic acid, formic acid and benzyl alcohol. Reports of the Scientific Committee for Food, Thirty-Fifth Series. BENZENECARBOXYLIC ACID, BENZENEFORMIC ACID, BENZENEMETHANOIC ACID, BENZOIC ACID, BENZOIC ACID,, CARBOXYBENZENE, DRACYCLIC ACID, PHENYLCARBOXYLIC ACID, and PHENYLFORMIC ACID Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Food Contact Materials (AFC) on a request from the Commission on the results of the study by McCann et al. The pressure of the liquid discharged from the reactor is reduced to atmospheric, and unreacted toluene is recovered. EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The available data on absorption, distribution, metabolism and excretion in animals and humans indicate that benzoic acid and its sodium and potassium salts are rapidly absorbed, primarily in the proximal part of the gastrointestinal tract, after oral administration. Do not allow solid to become airborne.

Information on the stability of the salts of the benzoic acid in food is very limited, but the benzoate anion is chemically stable, and degradation in food or reactions with food components are not anticipated, with the exception of the reaction with ascorbic acid under certain conditions (see benzoic acid hazards below). This study showed no effect on growth, fertility, lactation or survival, and provided a NOAEL, for both the parental animals and the offspring, of 500 mg benzoic acid/kg body weight per day, the highest dose tested.

JECFA (Joint FAO/WHO Expert Committee on Food Additives), 2002. Codex Alimentarius, an international treaty dictating food safety standards, limits the amount of benzoic acid or sodium benzoate to 0.05 to 0.1 percent by volume. Cranberries contain as much as 300-1300 mg free benzoic acid per kg fruit 1). The developmental toxicity studies in rats with sodium benzoate in the diet, showed NOAELs of 500 mg/kg bw per day (the highest dose tested) and 1310 mg/kg body weight per day, respectively, comparable to or higher than the NOAEL of 500 mg/kg bw per day in the dietary multigeneration reproductive toxicity in rats with benzoic acid. Material Safety Data Sheet Benzoic acid MSDS# 02720 Section 1 - Chemical Product and Company Identification MSDS Name: Benzoic acid Catalog Numbers: AC149130000, AC149130010, AC149130025, AC221800000, AC221800010, AC221802500 AC221802500, AC423470000, AC423470020, AC423470250, AC423475000, A63-500, A65-500, A68-30 Synonyms:

Benzoic acid is included in the European Union list of flavorings. Some probably aren't as safe as you'd hope. Dust/air mixtures may be explosive above the flash point.

Especially since this chemical is a potential environmental hazard. Summary record of the Standing Committee on the Food Chain and Animal Health. Japan Ministry of Health, Labour and Welfare. 1-13.

Finally, run a fan and deep clean the area. This results in exceedance of the group acceptable daily intake (ADI) in toddlers and children for the non-brand-loyal scenario. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … The studies performed by Chang and Ku 39), Gardner and Lawrence 40) and McNeal et al.

Benzoic acid and its calcium, potassium and sodium salts. In a developmental toxicity study in rats with benzoic acid by gavage, a no observed adverse effect level (NOAEL) of 160 mg benzoic acid/kg body per day was observed for maternal and developmental toxicity The developmental toxicity studies in rats with sodium benzoate in the diet showed a no observed adverse effect level (NOAEL) of 500 mg/kg body weight per day comparable to the NOAEL of the dietary four-generation reproductive toxicity in rats with benzoic acid. Small amounts of phthalic acid can also be present. Benzoic acid and its sodium and potassium salts are rapidly absorbed after oral administration. The European Food Safety Authority Panel noted that the available carcinogenicity studies on benzoic acid and its salts did not indicate any carcinogenic potential, although they were not conducted in accordance with current test guidelines and had deficiencies both in terms of design and reporting. Furthermore, anaphylaxis and urticaria have also been observed in sensitive individuals following exposure to benzoic acid and its salts at doses below the acceptable daily intake (ADI). doi:10.2903/j.efsa.2008.660. Opinion of the Scientific Committee on Cosmetic Products and Non-Food Products Intended for Conumers concerning benzoic acid and sodium benzoate. That’s why you need to know the facts about benzoic acid safety. Safety Precautions when Handling Benzoic Acid. Joint FAO/WHO Expert Committee on Food Additives reviewed benzoic acid as a flavoring substance at its 59th meeting, as one of a group of benzyl derivatives, at which the group ADI of 0–5 mg/kg body weight for benzoic acid and related compounds was reconfirmed 25). Environmental Safety Significant amounts of benzoic acid and sodium benzoate are released into the environment, primarily into water and soil, from their uses as preservatives in food, mouthwashes and cosmetics, although benzoic acid occurs naturally in many plants. The findings may thus be relevant for specific individuals within the population, showing sensitivity to food additives in general or to food colors in particular 24).

BfR (Bundesinstitut für Risikobewertung [Federal Institute for Risk Assessment]), 2013. Steinbrenner N, Löbell-Behrends S, Reusch H, Kuballa T and Lachenmeier DW, 2010. The Panel concluded that from the use of benzoic acid-benzoates as food additives from direct addition to food, the group ADI was exceeded in the brand-loyal scenario for toddlers and children consuming on a regular basis flavored drinks. Benzol in Lebensmitteln – Ein Überblick. EFSA Journal 2011;10(12):2994, 140 pp.

Use only in a hood or well-ventilated area (P271). Food Technol. Take a look at this guide to learn about benzoic acid’s uses and chemical safety data. Food Chemistry and Toxicology 32(2): 103-112. The European Food Safety Authority Panel noted that benzene is a genotoxic carcinogen classified by the International Agency for Research on Cancer as carcinogenic to humans (Group 1) 47), that the World Health Organization (WHO) has derived a guideline value for benzene in drinking water of 10 μg/L 48), that according to the Council Directive 98/83/EC12 the maximum level of benzene in drinking water is 1 μg/L in the European Union and that the German Federal Institute for Risk Assessment considered that the concentration of benzene in beverages should be as low as reasonably achievable 49). Benzoic acid is a common ingredient in many common household items. Evaluation of certain food additives and contaminants. CEC, Luxembourg, 1996, 33-39. SANCO – D1(2007)D/412774. EFSA Journal 2016;14(3):4433 https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2016.4433, SCF (Scientific Committee on Food), 1994. The European Food Safety Authority Panel agreed with this conclusion. From the regulatory benzoic acid maximum level exposure assessment scenario, the main contributing food categories to the total mean exposure estimates for infants and toddlers were flavored fermented milk products. Do not eat, drink or smoke when using this product (P270). Still, you and your team should always practice safe handling methods when dealing with this chemical. International Programme on Chemical Safety (IPCS): Benzoic Acid and Sodium Benzoate. NLM (National Library of Medicine). The European Food Safety Authority Panel recommended that when benzoic acid or its salts and ascorbic acid are used together, consideration should be given to the storage of soft drinks and food contact materials to minimize the formation of benzene in beverages as low as reasonably achievable. Chang P and Ku K, 1993. Opinion on benzoic acid and its salts. The four-generation reproductive toxicity study with benzoic acid in the diet in rats was considered by the European Food Safety Authority Panel as the pivotal study, as this study was the longest exposure period as compared to the developmental studies. Benzoic acid is an environmental hazard if disposed of improperly. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9472 The results of short-term and subchronic studies on benzoic acid and its salts indicate that their toxicity is low. BENZENECARBOXYLIC ACID, BENZENEFORMIC ACID, BENZENEMETHANOIC ACID, BENZOIC ACID, BENZOIC ACID,, CARBOXYBENZENE, DRACYCLIC ACID, PHENYLCARBOXYLIC ACID, and PHENYLFORMIC ACID. Benzoic acid is also produced when gut bacteria process polyphenols (from ingested fruits or beverages). Final.

In 2008, the European Food Safety Authority Panel on Food Additives, Flavorings, Processing Aids and Food Contact Materials assessed the results of McCann et al. Copyright © 1985-2020Kelleher, Helmrich and Associates, Inc. All rights reserved. BAuA (Federal Institute for Occupational Safety and Health), 2011. The Scientific Committee on Food established a group acceptable daily intake (ADI) of 0–5 mg/kg body weight per day for benzoic acid and its salts, also including benzyl alcohol and related benzyl derivatives used as flavorings 5). Required fields are marked *. Toxicological evaluation of some food additives including anticaking agents, antimicrobials, antioxidants, emulsifiers and thickening agents.

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