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[Analysis of safety and nutritive value of protein isolated from alfalfa].

A study on immunological effects of L-canavanine. Uses Crops: Alfalfa is harvested as hay which is processed or fed directly to livestock, or for seed production. View abstract.

There is some scientific evidence that alfalfa might help lower cholesterol levels in people with high cholesterol. Experientia 5-15-1980;36(5):562-564. View abstract. Insufficient Evidence to Rate Effectiveness for... How to Lower Your Cholesterol & Save Your Heart. Prete PE. Eur J Herbal Med 1997;3:25-8. View abstract. Alfalfa extracts are used in baked goods, beverages, and prepared foods, and the plant serves as a commercial source of chlorophyll and carotene.Bora 2011, Duke 1985. Changes in intestinal cellular morphology were noted in rats fed alfalfa; these effects were more extensive in animals fed whole plant material compared with sprouts. Taking alfalfa along with birth control pills might decrease the effectiveness of birth control pills. Diabetes: Alfalfa might lower blood sugar levels. Visit the FDA MedWatch website or call 1-800-FDA-1088. It is also used for high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, upset stomach, and a bleeding disorder called thrombocytopenic purpura. View abstract. J.Food Prot. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. 1972;29(1):1-9. Alfalfa might have some of the same effects as estrogen. View abstract. Alfalfa grows to approximately 1 m with 5 to 15 stems. View abstract. Alfalfa has been used for numerous ailments in traditional folk medicine throughout the ages. 2003;66(2):175-181. Alfalfa contains as many as 8 digestive enzymes and can be used to remedy indigestion, gas and bloating, nausea, gastritis and to stimulate the appetite. View abstract. Farnsworth, N. R. Alfalfa pills and autoimmune diseases. View abstract. 2003;69(1):548-553.

The health benefits of vitamin K – A review. Alfalfa leaves are POSSIBLY SAFE for most adults. Diet-induced systemic lupus erythematosus (SLE) in primates. Canavanine levels decrease as the plant matures. Stochmal, A., Piacente, S., Pizza, C., De Riccardis, F., Leitz, R., and Oleszek, W. Alfalfa (Medicago sativa L.) flavonoids. The toxicity of L-canavanine is mainly due to its structural similarity to arginine; it binds to arginine-dependent enzymes interfering with their action. 1989;35(5-6):287-298. Documented adverse effects of alfalfa during pregnancy include possible uterine stimulation.Brinker 1998, Ernst 2002 Although alfalfa has been anecdotally recommended to stimulate milk production, evidence is lacking.Forinash 2012, Agents with antiplatelet properties: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of agents with antiplatelet properties. View abstract. Strapp, C. M., Shearer, A. E., and Joerger, R. D. Survey of retail alfalfa sprouts and mushrooms for the presence of Escherichia coil O157:H7, Salmonella, and Listeria with BAX, and evaluation of this polymerase chain reaction-based system with experimentally contaminated samples. A trained scuba diver and researcher, Thor's has a keen interest in nature conservation and animal/plant protection. J.Agric.Food Chem. (2) If taking supplementary tablets is not your thing, alfalfa can be made into a pleasant tea that can really … 1. Comparative effects of alfalfa saponins and alfalfa fiber on cholesterol absorption in rats. Regression of atherosclerosis during cholesterol feeding in.

Bleeding may occur. A reduction in the formation of fatty streaks in the right and left coronary arteries and the aorta was also noted in animals receiving a diet supplemented with alfalfa.Asgary 2008, In addition to demonstrating a cholesterol-lowering effect, alfalfa administration was also found to exert hepatoprotective effects in rats intoxicated by carbon tetrachloride as noted by the ability to suppress increases in glutamic-oxaloacetic transaminase, glutamic pyruvic transaminase, gamma-glutamyl transferase, alkaline phosphatase, and bilirubin contents.Al-Dosari 2012, The addition of alfalfa seeds to the diet of 15 patients with type 2 hyperlipoproteinemia helped normalize serum cholesterol concentrations in 1 study.Mölgaard 1987.

Alfalfa might also cause some people's skin to become extra sensitive to the sun. Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more.

The biological effects and mode of action of L-canavanine, a structural analogue of L-arginine. Consider therapy modification.Mousa 2010, Stanger 2012, Spolarich 2007, Ulbricht 2008, Alfalfa seeds and sprouts can be contaminated with pathogens such as S. enterica and E. coli.CDC 1997, Christy 1999, Mahon 1997, Van Beneden 1999 Most healthy adults exposed to Salmonella or E. coli will have symptoms such as diarrhea, nausea, abdominal cramping, and fever that are self-limiting. View abstract. Alfalfa might decrease blood sugar.

Am J Clin Nutr. 1982;11(2):106-118. Roberts JL, Hayashi JA. Foster, Steven: 101 Medicinal Herbs. Some drugs that cause photosensitivity include amitriptyline (Elavil), Ciprofloxacin (Cipro), norfloxacin (Noroxin), lomefloxacin (Maxaquin), ofloxacin (Floxin), levofloxacin (Levaquin), sparfloxacin (Zagam), gatifloxacin (Tequin), moxifloxacin (Avelox), trimethoprim/sulfamethoxazole (Septra), tetracycline, methoxsalen (8-methoxypsoralen, 8-MOP, Oxsoralen), and Trioxsalen (Trisoralen). Malinow MR, McLaughlin P, et al. Many people use alfalfa hay as a mulch material as it acts like a natural fertilizer layer and weed blocker. 2001;49(2):753-758. View abstract. But alfalfa meal is a bit more processed than straight alfalfa … Warfarin (Coumadin) is used to slow blood clotting. Alfalfa tablets have been associated with the reactivation of SLE in at least 2 patients. By clicking “Accept”, you consent to the use of ALL the cookies. View abstract. Bleeding may occur. 2003;9(4):474-479. Autoimmun.Rev 2006;5(6):429-435. Because of its high vitamin K content, alfalfa may antagonize and therefore reduce the effects of warfarin. Rheum Dis Clin North Am 1991;17:323-32. Cookson, F. B. and Fedoroff, S. Quantitative relationships between administered cholesterol and alfalfa required to prevent hypercholesterolaemia in rabbits. Consider therapy modification.Mousa 2010, Stanger 2012, Spolarich 2007, Ulbricht 2008, Estrogen derivatives: Herbs (estrogenic properties) may enhance the adverse/toxic effect of estrogen derivatives. J Natl.Cancer Inst. Arginine reduces the toxic effects of canavanine in vitro.Natelson 1985 Further, canavanine may be metabolized to canaline, an analog of ornithine, that may inhibit pyridoxal phosphate and enzymes that require the B6 cofactor.Mölgaard 1987 L-canavanine has also been shown to alter intercellular calcium levelsMorimoto 1989 and the ability of certain B- or T-cell populations to regulate antibody synthesis.Prete 1985, Morimoto 1990 Alfalfa tablets have been associated with the reactivation of SLE in at least 2 patients.Roberts 1983. However, taking alfalfa seeds long-term is LIKELY UNSAFE. Morimoto, I.

View abstract. Chemistry. Elakovich, S. D. and Hampton, J. M. Analysis of coumestrol, a phytoestrogen, in alfalfa tablets sold for human consumption. Akaogi, J., Barker, T., Kuroda, Y., Nacionales, D. C., Yamasaki, Y., Stevens, B. R., Reeves, W. H., and Satoh, M. Role of non-protein amino acid L-canavanine in autoimmunity. J.Food Prot. View abstract. Polacheck, I., Zehavi, U., Naim, M., Levy, M., and Evron, R. Activity of compound G2 isolated from alfalfa roots against medically important yeasts. Alcocer-Varela J, Iglesias A, Llorente L, Alarcon-Segovia D. Effects of L-canavanine on T cells may explain the induction of systemic lupus erythematosus by alfalfa. In 1995 to 1996, 133 patients in Oregon and British Columbia developed salmonellosis from ingesting alfalfa sprouts contaminated with S. enterica (serotype Newport).Van Beneden 1999 Also in 1995, 242 patients in the United States and Finland developed salmonellosis from ingesting alfalfa sprouts contaminated with S. enterica (serotype Stanley).Mahon 1997, In June and July 1997, simultaneous outbreaks of E. coli 0157:H7 infection in Michigan and Virginia were independently associated with the ingestion of alfalfa sprouts grown from the same seed lot.CDC 1997 The FDA issued an advisory indicating that children, the elderly, and people with compromised immune systems should avoid eating alfalfa sprouts.Christy 1999, Because of its high potassium content, alfalfa may cause hyperkalemia.Munar 2007, Although alfalfa is listed as generally recognized as safe (GRAS) in the United States,van Wyk 2004 there are some concerns. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Monitor therapy.Hui 2009, Nonsteroidal anti-inflammatory agents: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of nonsteroidal anti-inflammatory agents. Alfalfa extracts are used in baked goods, beverages, and prepared foods, and the plant serves as a commercial source of chlorophyll and carotene.Bora 2011, Duke 1985, Dried alfalfa leaves are ground and sold as tablets or powder for use as nutritional supplements.

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